Читать книгу Gastrointestinal Pathology - Группа авторов - Страница 70

This uncommon and poorly characterized condition is histologically defined as the presence of dense lymphocytic infiltrates involving the esophageal mucosa without concomitant evidence of significant active inflammation. It is described in approximately 1/1000 esophageal biopsies, predominantly affecting older females (median age 63 years). This controversial entity lacks clearly defined clinical associations in adults, and likely represents a nonspecific reaction pattern to a wide variety of mucosal insults (Table 2.6), including GERD, medications, infection, motility disorders, and other immune‐mediated disorders. In the pediatric population, lymphocytic esophagitis has been described in association with Crohn’s disease and celiac disease.