Читать книгу Advances in Radiation Therapy - Группа авторов - Страница 41

In cancer tissue, a typical misbalance between the rate of cell death and the rate of cell proliferation occurs, resulting in tumor growth. Generally, within tumor categories the tumors with the highest proliferation rate have (without treatment) the worst prognosis [12], although conflicting study results have been published [46]. Generally, a higher proliferation rate before treatment and early during treatment may be related to a worse response to radiotherapy [8, 16], and especially accelerated proliferation during the course of radiotherapy is related to a poorer outcome.