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SLNs are colloidal drug delivery systems composed of physiological and biodegradable lipids. Structurally, they are spherical in shape with a lipid content between 1 and 30% [54]. SLNs have gained popularity and superiority to other delivery systems due to their controlled release of actives, higher drug entrapment efficiency for lipophilic drugs, enhanced drug stability, as well as protection of labile substances from chemical degradation, photo degradation, hydrolysis, and oxidation [55]. Moreover, their nano-size ensures enhanced contact with and penetration of the epidermis. SLNs possess UV protection and occlusive properties preventing transepidermal water loss. All of these unique properties make SLNs attractive carriers for skin delivery of cosmeceutical ingredients. Examples of actives delivered via SLNs include hydroquinone, adapalene, and curcuminoids [56–59].