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Niosomes are nonionic unilamellar or multilamellar vesicles in which the active ingredient is encapsulated. They have improved the stability and availability of active ingredients as well as skin penetration compared to liposomes. Examples of drugs delivered using niosomes are minoxidil and ellagic acid [44]. The synergistic effects of two antioxidants, α-tocopherol and curcumin, were demonstrated using a niosomal delivery system [45].

Ultrasomes are liposomes encapsulating a UV-endonuclease enzyme [46]. They help repair UV-induced DNA damage and inhibit the expression of pro-inflammatory cytokines. Similarly, photosomes help repair DNA damage by encapsulating a light-activated enzyme (photolyase) in a liposomal structure and are thus included in certain sunscreen products.