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Whole‐genome sequencing is the process of determining the entire DNA sequence of an organism at one time. It provides detailed information regarding an organism's genetic makeup, including mutations and functional variations in DNA. Also known as “next‐generation (nex‐gen) sequencing,” this research technique is growing in popularity and may represent a new gold standard in DNA analysis. The technique provides such detailed information about an individual organism that the information can be used to create targeted drug therapy. Because exons provide the information for making proteins, whole‐exome sequencing provides information on variations in the protein‐coding regions of many genes at one time and is an efficient way to study disease‐causing mutations. Whole‐genome sequencing provides a way to study those diseases caused by mutations occurring outside of exons (Abdelbary et al. 2017; Mardis 2013). It is being used to study mutations in microbes that promote drug resistance and survival within the host (Abdelbary et al. 2017). This may represent a way to identify and develop targeted antimicrobial therapy in the future.