Читать книгу Pathology of Genetically Engineered and Other Mutant Mice - Группа авторов - Страница 45

OMIM is a comprehensive database on human genes and genetic disorders and has been publicly available since 1987 [74]. OMIM is continually updated from the public literature and has links to other species databases. OMIM is the internet version of the multivolume book titled Mendelian Inheritance in Man by Victor McCusik [75] and is based at Johns Hopkins University. OMIM entries are classified using a standardized system of MIM numbers (denoting genetic classifications) and OMIM disorder codes (indicating loci associated genetic based diseases). OMIM concentrates on the genotype/phenotype relationship. OMIM entries contain text summaries of associated clinical features, molecular genetics, references, clinical synopses, phenotypic series the entry belongs to, and multiple graphic representations of the data [74]. Information and references on various animal models, including those in mice, that mimic or are confirmed orthologs is provided.