Читать книгу Manual of Equine Anesthesia and Analgesia - Группа авторов - Страница 290

 The TGF is a local intrarenal negative feedback mechanism, and is important in regulating the GFR and urine excretion rate.

 Within the distal convoluted tubule, specialized cells called the macula densa sense decreased sodium chloride concentrations within the tubular lumen.

 This results in a cascade of events resulting in renin release (see Figure 5.2).

 The tone of the glomerular arterioles is adjusted to control GFR.

 Nitric oxide and adenosine are thought to have an important role in this mechanism.