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 Angiotensin II has a short half‐life (one to two minutes) in plasma.It is degraded by peptidases into angiotensin III and IV.

 Angiotensin III has an effect which is equipotent to angiotensin II in causing the release of aldosterone, but has less potent pressor effects.

 Angiotensin IV has decreased systemic effects compared to angiotensin II, but has multiple functions in the nervous system.