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Effects of Angiotensin II

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 It is a potent vasoconstrictor, directly increasing blood pressure by constricting systemic arterioles.

 It increases sodium reabsorption, leading to fluid retention and increased extracellular fluid volume.

 Catecholamines are released from the adrenal medulla, secondarily affecting systemic blood pressure.

 It diminishes the sensitivity of the baroreceptor reflex leading to an increase in blood pressure.

 It increases thirst via its effect on the hypothalamus.

 It increases the release of ADH. This leads to the insertion of aquaporin channels in the cell membranes of the collecting duct, causing increased water reabsorption.

Manual of Equine Anesthesia and Analgesia

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