Читать книгу Manual of Equine Anesthesia and Analgesia - Группа авторов - Страница 303

 Most inhalational anesthetics have dose‐dependent effects on renal function.

 In general, RBF is decreased.

 All inhalants decrease GFR.

 Urine production decreases with inhalational anesthetics, which increase secretion of ADH and favors fluid retention in the extravascular space.

 Light planes of inhalational anesthesia can preserve renal autoregulation.

  Renal vascular resistance increases with most anesthetics.

 Nephrotoxicity is mainly a problem with “older” inhalants (e.g. methoxyflurane).Non‐steroidal anti‐inflammatory drugs (NSAIDs) and some antibiotics (e.g. aminoglycosides, tetracyclines) potentiate the nephrotoxicity of inhalants.