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Aldosterone inhibitors (e.g. spironolactone)
ОглавлениеBlock effects of aldosterone on aldosterone‐receptors leading to reduced Na+ reabsorption.
This results in more sodium and water passing into the collecting duct and being excreted.
The potassium sparing results from inhibiting sodium reabsorption which causes less K+ and H+ to be exchanged for Na+, and thus not lost in the urine.