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Aldosterone inhibitors (e.g. spironolactone)

Оглавление

 Block effects of aldosterone on aldosterone‐receptors leading to reduced Na+ reabsorption.

 This results in more sodium and water passing into the collecting duct and being excreted.

 The potassium sparing results from inhibiting sodium reabsorption which causes less K+ and H+ to be exchanged for Na+, and thus not lost in the urine.

Manual of Equine Anesthesia and Analgesia

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