Читать книгу Pathy's Principles and Practice of Geriatric Medicine - Группа авторов - Страница 152

Inflammation is a common hallmark of brain ageing and diseases. Neuroinflammation is mediated by diverse cytokines, chemokines, reactive oxygen species, and secondary messengers produced by resident glial cells (i.e. microglia and astrocytes), endothelial cells, and peripheral immune cells. Despite exerting a potentially protective role, such inflammatory responses can have negative consequences such as oedema, tissue damage, and cell death.^23,29