Читать книгу Pathy's Principles and Practice of Geriatric Medicine - Группа авторов - Страница 425

A Cochrane Review of supplementation studies in participants without AMD considered five RCTs investigating vitamin C, vitamin E, beta‐carotene, and MVM supplements (Centrum Silver®).²⁴ The authors concluded that neither vitamin E (four studies) nor beta‐carotene (two studies) nor vitamin C (one study) prevented AMD. However, the study of MVM showed an increased risk of any AMD. Other adverse effects were not consistently reported, but one of the studies of vitamin E supplements showed an excess of haemorrhagic strokes, and there is evidence from other large studies that supplements of beta‐carotene increase the risk of lung cancer in those who smoke or who have been exposed to asbestos.