Читать книгу Animal Behavior for Shelter Veterinarians and Staff - Группа авторов - Страница 134

Hypothyroidism is one of the endocrinopathies most often mentioned as being associated with behavioral changes in dogs. However, there are minimal data supporting any causal association between hypothyroidism and aggression. One study compared the analytes commonly used to evaluate thyroid function between dogs with and without aggression toward people and found no difference between the two groups (Radosta et al. 2012). A double‐blind placebo‐controlled trial evaluated the effect of six weeks of thyroid replacement on owner‐directed aggression in 29 normal dogs with borderline low thyroid values and found no difference between the treatment and control groups (Dodman et al. 2013). In another study of 20 hypothyroid dogs without diagnosed behavior problems, treatment with levothyroxine resulted in no behavioral change other than increased activity levels (Hrovat et al. 2018). Serotonin and prolactin levels were also measured prior to, at six weeks, and six months after the initiation of levothyroxine therapy, and no significant changes in levels were noted (Hrovat et al. 2018). Thus, at this time, there are no data to support the proposal that thyroid supplementation may benefit behavioral therapy in dogs.