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Bacteria

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Suppurative meningitis is most common in neonatal animals, especially those with failure of passive transfer of immunoglobulin. Often there is considerable protein exudate with tissue swelling. When subacute to chronic accumulations of predominantly polymorphonuclear inflammatory cells become sectioned off from CNS parenchyma with astrofibrosis, then a true brain abscess is formed and can act as a space‐occupying lesion causing compression and edema of adjacent tissue. Because of the rigidity of the calvaria, these forms of brain swelling can result in herniation of adjacent parts of the brain (Figures 4.7 and 4.8).30 Vertebral osteomyelitis most often causes spinal cord compression rather than myelitis, and at least initially even septic emboli damage CNS tissue because of ischemic and hemorrhagic infarction.

Large Animal Neurology

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