Читать книгу Large Animal Neurology - Joe Mayhew - Страница 93

Type I, anaphylactic immune responses in the CNS are rare, partly because the CNS is a relatively privileged site, somewhat isolated from the immune system. Cytotoxic, autoimmune, type II reactions directed against natural or altered antigens such as myelin do occur in the CNS and PNS, causing nonsuppurative encephalitis or neuritis, respectively. Antigen–antibody complex, type III mediated vasculitis occurs in the CNS in some diseases, and, like other forms of vasculitis, CNS damage results more from infarction than from inflammation. The latter can be neutrophilic, lymphocytic, or mixed.