Читать книгу Low-Carb Diet For Dummies - Katherine B. Chauncey - Страница 52

Studies suggest that abdominal fat causes fat cells to release pro-inflammatory chemicals, which can make the body less sensitive to the insulin it produces by disrupting the function of insulin-responsive cells and their ability to respond to insulin. This is known as insulin resistance — the hallmark of type 2 diabetes. Having excess abdominal fat (that is, a large waistline) is known as central or abdominal obesity, a particularly high-risk form of obesity. Metaflammation is the metabolic inflammatory state associated with obesity. The condition is defined by low-grade chronic inflammation in metabolic tissues, including adipose (fat) cells, liver, brain, and pancreas. Weight loss and calorie restriction have shown to decrease inflammation and increase insulin sensitivity in people who have been medically advised to lose excess weight.