Читать книгу Routes to Essential Medicines - Peter J. Harrington - Страница 70

Dermatological Medicines/Medicines Affecting Skin Differentiation and Proliferation

Discussion. Benzoyl peroxide is formed by reaction of benzoyl chloride with hydrogen peroxide.

Dry (98%) benzoyl peroxide is a very dangerous material!

Benzoyl peroxide is not purified by crystallization.

Benzoyl peroxide melts with decomposition and may explode at 106° C.

Benzoyl peroxide may explosively decompose on shock, friction, or concussion.

Benzoyl peroxide is a strong oxidant and reacts violently with combustible or reducing materials.

Benzoyl peroxide reacts violently with inorganic acids, organic acids, alcohols, and amines.

Benzoyl peroxide (75%, with 25% added water) has a better safety profile.