Читать книгу Essential Endocrinology and Diabetes - Richard I. G. Holt - Страница 2

1  Cover

2  Title Page

3  Copyright Page

4  Preface

5  List of abbreviations

6  Part 1: Foundations of Endocrinology CHAPTER 1: Overview of endocrinology A brief history of endocrinology and diabetes The role of hormones Classification of hormones Control systems regulating hormone production Endocrine disorders CHAPTER 2: Basic cell biology and hormone synthesis Chromosomes, mitosis and meiosis Synthesizing a peptide or protein hormone Synthesizing a hormone derived from amino acids or cholesterol Hormone transport CHAPTER 3: Molecular basis of hormone action Cell‐surface receptors Nuclear receptors CHAPTER 4: Investigations in endocrinology and diabetes Pre‐analytical requirements for accurate endocrine testing Laboratory assay platforms Reference ranges Static and dynamic testing Cell and molecular biology as diagnostic tools Imaging in endocrinology

7  Part 2: Endocrinology – Biology to Clinical Practice CHAPTER 5: The hypothalamus and pituitary gland Embryology and anatomy Pituitary tumours The hypothalamus The hypothalamic–anterior pituitary hormone axes The anterior pituitary hormones Hypopituitarism Hormones of the posterior pituitary CHAPTER 6: The adrenal gland The adrenal cortex The adrenal medulla CHAPTER 7: Reproductive endocrinology Embryology of the reproductive organs The male reproductive system The female reproductive system Pubertal disorders Subfertility CHAPTER 8: The thyroid gland Embryology Anatomy and vasculature Thyroid hormone biosynthesis Circulating thyroid hormones Function of thyroid hormones Thyroid function tests Clinical disorders CHAPTER 9: Calcium and metabolic bone disorders Calcium Hormones that regulate calcium Clinical disorders of calcium homeostasis Bone health and metabolic bone disease Clinical conditions of bone metabolism Vitamin D deficiency, osteomalacia and rickets CHAPTER 10: Pancreatic and gastrointestinal endocrinology and endocrine neoplasia Pancreatic endocrinology Gastrointestinal endocrinology and associated clinical conditions Endocrine tumour predisposition syndromes Tumours with ectopic hormone production Hormone‐sensitive tumours Other tumours relevant to endocrinology

8  Part 3: Diabetes and Obesity CHAPTER 11: Overview of diabetes A brief history of diabetes and its classification Classification of diabetes Diagnosis of diabetes Insulin Glucagon CHAPTER 12: Type 1 diabetes What is type 1 diabetes? Epidemiology Pathogenesis Aetiology Clinical features Diagnosis Management of type 1 diabetes Acute metabolic emergencies CHAPTER 13: Type 2 diabetes Epidemiology Pathophysiology Prognosis Clinical features Prevention of diabetes Screening for diabetes Management of type 2 diabetes CHAPTER 14: Complications of diabetes Introduction Microvascular complications Pathology of microvascular complications Pathogenesis of microvascular complications Clinical features of microvascular complications Diabetes‐related kidney disease Neuropathy The diabetic foot Genitourinary and sexual problems of diabetes Atherosclerotic cardiovascular disease Heart failure Cancer Non‐alcoholic fatty liver disease Gastro‐intestinal tract Bone and Joint Skin disorders Psychological and psychiatric sequelae of diabetes Diabetes and pregnancy Social sequelae of diabetes Organization of diabetes care CHAPTER 15: Obesity Introduction What is obesity? The health and social consequences of overweight and obesity Regulation of body weight The causes of obesity Genetic factors Environmental changes Prevention of obesity Management of the individual with obesity Conclusions

9  Index

10  End User License Agreement