Читать книгу Autoimmune Liver Disease - Группа авторов - Страница 81

IL‐19, IL‐20 and IL‐24 signal through the IL‐20RA/RB receptor complex [26]. Theses cytokines are expressed by both immune and epithelial cells and result in bilateral stimulation. These cytokines have a dual potential to immunoregulate innate and adaptive immune responses or to promote immunopathogenesis. These cytokines are most often pathogenic in autoimmune diseases, perpetuating chronic tissue inflammation.