Читать книгу The SAGE Encyclopedia of Stem Cell Research - Группа авторов - Страница 401

Human embryonic stem cells (hESCs) are omnipotent or pluripotent cells derived from pre-implantation-stage embryos. These cells have been intensively investigated for their potential use in cardiac regeneration, and several pre-clinical trials have found that hESCs differentiate into contractile cardiomyocytes in vitro. Clinical application of hESCs is controversial due to ethical issues, immunological incompatibility, and risk of teratoma formation. As of 2014, no U.S. clinical trials with hECSs have begun.