Читать книгу The SAGE Encyclopedia of Stem Cell Research - Группа авторов - Страница 407

Hematological cancers are malignancies affecting all blood cells, bone marrow, and the lymphatic system. The number of people suffering from such malignancies has helped to generate a great deal of interest in the research for treatment, many of which are going into clinical trials to test for new approaches for treatment of hematological cancers. The hematopoietic stem cells found in the bone marrow can differentiate into all types of blood cells (white blood cells, platelets, and red blood cells) and have proven useful for the treatment of some blood malignancies such as some forms of leukemias. Hematopoietic stem cells are used by health professionals to rescue the effect of chemotherapy on blood cells. Currently, approaches and methods are being looked at by researchers for ways to improve the use of stem cells in the treatment of cancer and to find new methods for stem cell use in the treatment of cancers. Many clinical trials are currently ongoing around the world, most especially in the United States.

The list of hematological cancers treated with stem cells is extensive and includes acute lymphoblastic leukemia (ALL), acute biphenotypic leukemia, acute undifferentiated leukemia, acute myelogenous leukemia (AML), chronic myelogenous leukemia (CML), chronic lymphocytic leukemia (CLL), juvenile chronic myelogenous leukemia (JCML), juvenile myelomocytic leukemia (JMML), and non-Hodgkin’s lymphoma and Hodgkin’s disease. Though several types of stem cells are being utilized or investigated for cancer treatment, hematopoietic stem cells are the preferred choice for the treatment of hematological cancers.