Читать книгу The SAGE Encyclopedia of Stem Cell Research - Группа авторов - Страница 417

Approximately 71% of patients lacking HLA-identical siblings to donate stem cells for their transplant utilize haploidentical stem cells. However, there is a risk of more potent graft-versus-tumor effect and severe graft-versus-host disease that may be induced by this type of stem cell. There is a current trial investigating stem cell transplant using partially mismatched donor cells in treatment of hematological cancers. The investigators are hoping to test two kinds of transplants: a transplant with a full-intensity dose of radiotherapy and chemotherapy, and reduced-intensity doses of chemotherapy and radiotherapy. The study will be investigating the overall survival rate in patients with hematological cancers.