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An approximate trend in the skin surface pH development during childhood is presented in Figure 3 (adapted from [4]). Independent from gestational age and birth weight, pH decreases in a steep manner in the weeks of the postnatal life and then more gradually in the rest of the neonatal period [39, 40]. The mean pH value from 6 different body sites in the first day of life (full-term neonate) was 7.08, being significantly elevated compared to adult controls (5.7) [41]. During the next day, a decrease in surface pH was already notable in neonates but still significantly higher than that in adults. The lowering in pH from days 3 to 30 of the neonatal period was most prominent in the volar forearm region compared to the forehead, cheek, and buttock [37]. The pH values remained stable later in infancy (days 30 and 90) for all tested skin sites. Later in infancy, skin surface acidity appears to be similar to that in adults [38]. A single report demonstrated significantly higher pH values (both buttock and volar forearm skin) in infants aged 8–24 months when compared to adults [1]. No differences were noted between groups after splitting the infants into 2 age categories: 8–12 and 12–24 months.