Читать книгу Pathology of Genetically Engineered and Other Mutant Mice - Группа авторов - Страница 14

The pathology of mice in research was first led by Thelma Dunn and Harold Stewart at the National Cancer Institute (NCI) at the NIH [11–13]. Both were MD pathologists who applied general rules of human pathology diagnosis to mice when possible. Although mouse pathology nomenclature does not follow any official designation, two organizations (INHAND; https://www.toxpath.org/inhand.asp and National Cancer Institute Mouse Models of Cancer Consortium Tumor Pathology Nomenclature) have provided international nomenclatures for specific tissues [2, 14]. Other published guides are included in each appropriate organ chapter [15, 16]. Many books and refereed publications on mouse pathology provide valuable information for pathologists and scientists [12,17–35] as well as web sites (https://ntp.niehs.nih.gov/nnl; http://www.informatics.jax.org/frithbook; http://eulep.pdn.cam.ac.uk/~skinbase/index.php). Importantly, many of these references involve both DVMs and MDs, pathologists, and basic scientists, who integrate mouse and human disease nomenclature together to be state‐of‐the‐art. The pathology nomenclature used in this book generally reflects the NCI tumor pathology and INHAND general pathology nomenclatures. There are, however, no international or national standards for nomenclature that must be followed. These published nomenclatures are merely guidelines for use by scientists, pathologists, and journals. Each chapter author considered these guidelines and noted appropriate references for each organ and tissue.