Читать книгу Biomolecular Engineering Solutions for Renewable Specialty Chemicals - Группа авторов - Страница 73

Cells are regulated at different checkpoints by the interactions of various cyclins and cyclin‐dependent kinases (CDKs). Before the progression to the next phase of the cell cycle, cell growth is regulated at each checkpoints by cyclin and CDKs. In cell cycle regulation, cyclin, CDKs, and p53 play a key role. Recently, vanilla has shown its potential to arrest cell cycle in colorectal cancer cells at the G1/G0 stage at lower concentration (200 μg/ml), and G2/M arrest occurs at higher concentration of vanillin (1000 μg/ml) (Ho et al., 2009).