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B Distribution of blood flow in lung

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 The distribution of pulmonary blood flow within the lung of the horse was previously thought to be primarily influenced by gravity; however, there is not a consistent vertical gradient to blood flow in the lungs of horses.

 This implies that gravity does not play a major role in blood flow distribution.

 Endogenous vasoactive mediators (e.g. nitric oxide and endothelin‐1) are now thought to play a major role in the distribution of perfusion within the lung.

Manual of Equine Anesthesia and Analgesia

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