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I Oxygen binding to Hb

Оглавление

 Several factors can influence the binding of O2 to hemoglobin.

 The O2‐Hb dissociation curve demonstrates the relationship between PO2 and saturation of Hb with oxygen (SO2) (see Figure 4.5).A left‐shift to the curve indicates a higher affinity of Hb for O2 and thus a higher saturation at a given PaO2.A right shift in the curve results from a lower affinity of Hb for oxygen.

 The position of the curve is usually described by the position at which Hb is 50% saturated (P50).P50 is approximately 24 mmHg in the adult horse.

Manual of Equine Anesthesia and Analgesia

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