Читать книгу Drug Transporters - Группа авторов - Страница 111

MATE transporters have emerged as a novel and exciting route for the excretion of drugs, toxicants, and endogenous molecules. Full characterization of MATE transporters using contemporary structural biology approaches will aid in elucidating understanding of their molecular and biochemical activity. Likewise, further adaptation of MATE substrates in drug–drug interaction and pharmacogenetic studies will greatly advance the translatability of fundamental knowledge regarding this transporter family.