Читать книгу Drug Transporters - Группа авторов - Страница 68

2.11.2 Substrate and Inhibitor Selectivity

Оглавление

Limited information has been obtained on the transport function of CT2. In vitro, CT2 has been shown to be a bidirectional transporter of carnitine, its derivatives, and betaine; it appears to play a role in the transport of these compounds in the testes [76]. In addition, CT2 mediates the transport of the chemotherapeutic drug, doxorubicin [1], and the anticancer polyamine analogue bleomycin‐A5 in cancer cells [105].

Drug Transporters

Подняться наверх