Читать книгу Transfusion Medicine - Jeffrey McCullough - Страница 177

Granulocytes collected by centrifuge leukapheresis techniques demonstrate normal bacterial killing, phagocytosis, granulocyte metabolism), chemiluminescence, superoxide production, and chemotaxis [77, 84–86]. In vivo studies using isotope‐labeled cells showed that granulocytes have normal intravascular recovery and survival, and migrated to sites of inflammation [77, 87–89]. The use of corticosteroids or G‐CSF in donors to improve the granulocyte yield does not adversely affect their function in vitro or in vivo [75, 84, 87].