Читать книгу Complementary and Alternative Medicine (CAM) Supplement Use in People with Diabetes: A Clinician's Guide - Laura Shane-McWhorter - Страница 25

Fenugreek contains many different chemical components, including saponins and several glycosides.⁷⁵ The seeds contain alkaloids, including trigonelline, gentianine, and carpaine compounds. Fiber, 4-hydroxyisoleucine, and fenugreekine, components that may have hypoglycemic activity, are also found in the seeds. The mechanism is thought to involve delay of gastric emptying, slowing carbohydrate absorption, and inhibition of glucose transport.⁷⁷ Fenugreek may also increase the number of insulin receptors in red blood cells and improve glucose utilization in peripheral tissues; thus demonstrating potential antidiabetic effects in both the pancreas and other sites.⁷⁸ A constituent of the seeds, 4-hydroxyisoleucine, may directly stimulate insulin secretion.⁷⁹