Читать книгу Complementary and Alternative Medicine (CAM) Supplement Use in People with Diabetes: A Clinician's Guide - Laura Shane-McWhorter - Страница 30

Bitter melon contains several chemical ingredients, including the glycosides momordin and charantin. Polypeptide P, charantin, and vicine are the specific components thought to produce hypoglycemic effects.^75,85 Other possible mechanisms in diabetes include increased tissue glucose uptake, increased liver/muscle glycogen synthesis, inhibition of enzymes involved in glucose production (glucose-6-phosphatase, fructose-1, and 6-bisphosphatase), and enhanced glucose oxidation (by the glucose-6-phosphate dehydrogenase, or G6PDH, pathway).^75,85