Читать книгу Complementary and Alternative Medicine (CAM) Supplement Use in People with Diabetes: A Clinician's Guide - Laura Shane-McWhorter - Страница 36

Major side effects of ginseng include insomnia and restlessness. Worrisome side effects include increased blood pressure or heart rate. Headache is common, and ginseng may also cause mastalgia, mood changes, and nervousness. Ginseng is unsafe in infants and children, and may not be safe in pregnancy.⁹¹

Ginseng has been shown to decrease the effectiveness of the blood thinner warfarin (Coumadin),¹⁸ and protection against thromboembolic events is lost. Ginseng decreases the effects of diuretics and hypertension medications.¹⁹ In combination with certain antidepressants, ginseng has resulted in mania.¹⁹ With estrogens, ginseng may produce additive estrogenic effects.¹⁹ Ginseng may inhibit cytochrome P450 (CYP450) 2D6 isoenzymes involved in metabolism of drugs and result in increased effects of drugs such as certain analgesics and some antidepressants.¹⁹ When combined with insulin, sulfonylureas, or other secretagogues, ginseng may cause hypoglycemia.⁹¹