Читать книгу Complementary and Alternative Medicine (CAM) Supplement Use in People with Diabetes: A Clinician's Guide - Laura Shane-McWhorter - Страница 37

Ginseng has been frequently studied for physical performance or cognitive function as well as immune system effects, but there are few trials where it has been evaluated for diabetes. In one randomized, double-blind study of Asian ginseng in 36 newly diagnosed patients with type 2 diabetes, 12 people each were assigned to placebo, 100 mg/day, or 200 mg/day. Although baseline values were not reported, at the end of the 8-week study, fasting glucose for the three groups was 149 mg/dl (8.3 mmol/l), 139 mg/dl (7.7 mmol/l), and 133 mg/dl (7.4 mmol/l), respectively. (Results were significant only for the 100 mg/day group, P < 0.05.) Baseline values were not reported, and the average A1C levels at the end of the study were 6.5, 6.5, and 6%, respectively, for the three groups (P < 0.05 for the 200-mg group only).⁹⁹ The accuracy of the diagnosis of diabetes or problems with study design may have been an issue.

American ginseng has been studied in people with and without type 2 diabetes. In a small study, subjects with and without diabetes were given a 25-g OGTT, with 3 g ginseng or placebo.⁹² Ginseng was given right before or 40 minutes before the OGTT. In subjects without diabetes, there was no difference in postprandial glucose when ginseng was taken right before the OGTT, but when it was taken 40 minutes before, there was a significant decrease in postprandial glucose (P < 0.05 vs. placebo). In the participants with diabetes, postprandial glucose decreased whether ginseng was given right before or 40 minutes before the OGTT. The same group of researchers tried the same and higher doses of American ginseng: 3, 6, or 9 g ginseng versus placebo. Glucose decreased in all groups, and there was no difference in effect between the 3-, 6-, and 9-g doses of ginseng.⁹⁸