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Metronidazole is a nitroimidazole antibacterial and antiprotozoal agent used in the treatment of giardiasis, anaerobic infections and inflammatory bowel disease (Evans et al., 2003). Neurotoxicity from metronidazole has been reported in dogs receiving as low as 67 mg/ kg/day for an average of 3–14 days (Dow, 1989) or 60.3 mg/kg/day for 44.9 days (Evans et al., 2003), and in cats receiving 111 mg/kg/ day for 9 weeks or 58 mg/kg/day for 6 months (Caylor and Cassimatis, 2001).