Читать книгу Canine and Feline Epilepsy - Luisa De Risio - Страница 205

Treatment involves metronidazole discontinuation, symptomatic and supportive care. In dogs, diazepam has been reported to markedly improved recovery times of animals with metronidazole toxicosis. Diazepam was administered at an initial dose of 0.2–0.5 mg/kg IV followed by 0.3–0.5 mg/kg PO every 8 h for 3 days (Evans et al., 2003). Mean response time (defined as the time to resolution of the debilitating clinical signs) was 4.25 days for untreated dogs to 13.4 h for treated dogs, and mean recovery time (defined as the time to resolution of all residual clinical signs) was 11 days for untreated dogs and 38.8 h for treated dogs (Evans et al., 2003).