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Veterinary classification of seizures and epilepsies based on underlying aetiology Reactive seizures
ОглавлениеReactive seizures are the reaction of a normal brain to a systemic metabolic or nutritional disorder or exogenous toxin exposure (Podell et al., 1995). When the metabolic, nutritional or toxic disorder resolves, the animal does not have recurrent seizures, and therefore reactive seizures are not considered a form of epilepsy, per se (Jull et al., 2011). The authors feel that the term reactive seizure should continue to be used in veterinary medicine as the term ‘metabolic’ proposed by the ILAE 2010 may generate confusion by referring to metabolic disorders only leaving toxic and nutritional aetiologies poorly classified. In addition the term ‘metabolic’ has not been widely accepted by several expert epileptologists (Panayiotopoulos, 2012).
Animals with reactive seizures frequently have acute onset of bilateral symmetrical neurological deficits indicating diffuse fore-brain or intracranial involvement and concurrent signs of dysfunction of other body systems. Occasionally, seizures are the only obvious clinical abnormality. Aetiologies of reactive seizures are listed in Box 3.1 and described in detail in Chapter 4.