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Once hypoglycaemia is confirmed, emergency treatment of hypoglycaemia-induced seizures involves slow (over 15 min) intravenous administration of 0.5–1 ml/kg of 50% dextrose, diluted 1:2 or 1:4 with 0.9% saline or sterile water. This dosage may need to be repeated and a continuous infusion of 5% dextrose (e.g. 50 ml of 50% dextrose in 500 ml of 0.9% saline or sterile water) may be necessary to maintain normoglycaemia. If intravenous therapy is difficult to perform, oral administration of a rapidly absorbed source of sugar (such as honey, Karo corn syrup or maple syrup) can be a useful substitute. Feeding frequent small meals can also help maintain normoglycaemia. Supportive care of the seizuring animal should be performed as described in Chapter 24. Specific treatment for the underlying cause of hypoglycaemia should be provided.