164. | Toxicological Detection, | 140 |
| 2. Amylic Alcohol. | |
165. | Properties of Amylic Alcohol, | 140 |
166. | Experiments as to the Effect on Animals of Amylic Alcohol, | 140, 141 |
167. | Detection and Estimation of Amylic Alcohol, | 141 |
168. | Amyl Nitrite—Properties—Symptoms—Post-mortem Appearances, | 141 |
| IV. ETHER. | |
169. | Properties of Ethylic Ether, | 141, 142 |
170. | Ether as a Poison, | 142 |
171. | Fatal Dose, | 142 |
172. | Ether as an Anæsthetic, | 142, 143 |
173. | Separation of Ether from Organic Fluids, &c., | 143 |
| V. CHLOROFORM. | |
174. | Discovery of Chloroform—Properties, Adulterations, and Methods for Detecting them, | 143-145 |
175. | Methods of Manufacturing Chloroform, | 145, 146 |
| Poisonous Effects of Chloroform. | |
| 1. As a Liquid. | |
176. | Statistics, | 146 |
177. | Local Action, | 146 |
178. | Action on Blood, Muscle, and Nerve-Tissue, | 146 |
179. | General Effects of Liquid Chloroform—Illustrative Cases, | 146, 147 |
180. | Fatal Dose, | 147 |
181. | Symptoms, | 148 |
182. | Post-mortem Appearances, | 148 |
| 2. The Vapour of Chloroform. | |
183. | Statistics of Deaths through Chloroform—Anæsthesia, | 148, 149 |
184. | Suicidal and Criminal Poisoning—Illustrative Cases, | 149, 150 |
185. | Physiological Effects, | 150 |
186. | Symptoms witnessed in Death from Chloroform Vapour, | 150, 151 |
187. | Chronic Chloroform Poisoning—Mental Effects from Use of Chloroform, | 151, 152 |
188. | Post-mortem Appearances, | 152 |
189. | The Detection and Estimation of Chloroform—Various Tests, | 152, 153 |
190. | Quantitative Estimation, | 153 |
| VI. OTHER ANÆSTHETICS. | |
191. | Methyl Chloride—Methene Dichloride, &c., | 154 |
192. | Pentane, | 154 |
193. | Aldehyde, | 154 |
194. | Paraldehyde, | 154 |
| VII. CHLORAL. | |
195. | Chloral Hydrate; its Composition and Properties, | 154, 155 |
196. | Detection, | 155 |
197. | Quantitative Estimation of Chloral Hydrate, | 155, 156 |
198. | Effects of Chloral Hydrate on Animals—Depression of Temperature—Influence on the Secretion of Milk, &c., | 156, 157 |
199. | Action upon the Blood, | 157 |
200. | Effects on Man, | 157, 158 |
201. | Fatal Dose, | 158, 159 |
202. | Symptoms, | 159 |
203. | Action of Chloral upon the Brain, | 159 |
204. | Treatment of Acute Chloral Poisoning, | 160 |
205. | Chronic Poisoning by Chloral Hydrate, | 160, 161 |
206. | Manner in which Chloral is Decomposed in, and Excreted from, the Body, | 161, 162 |
207. | Separation from Organic Matters—Tests for Chloral, | 162, 163 |
| VIII. BISULPHIDE OF CARBON. | |
208. | Properties of Bisulphide of Carbon, | 163 |
209. | Poisoning by Bisulphide of Carbon, | 163 |
210. | Action on Animals, | 163, 164 |
211. | Chronic Poisoning by Bisulphide of Carbon—Effects on the Brain, &c., | 164, 165 |
212. | Post-mortem Appearances, | 165 |
213. | Separation and Detection of Carbon Bisulphide—Tests, | 165 |
214. | Xanthogenic Acid, | 165 |
215. | Potassic Xanthogenate, | 165 |
| IX. THE TAR ACIDS—PHENOL—CRESOL. | |
216. | Properties and Sources of Carbolic Acid, | 165, 166 |
217. | Different Forms of Carbolic Acid—Calvert’s Carbolic Acid Powder—Carbolic Acid Soaps, | 166, 167 |
218. | Uses of Carbolic Acid, | 167 |
219. | Statistics Relative to Poisoning by Carbolic Acid, | 167-169 |
220. | Fatal Dose, | 169 |
221. | Effects on Animals—Infusoria—Fish—Frogs, | 169, 170 |
222. | Effects on Warm-Blooded Animals, | 170 |
223. | Symptoms Produced in Man—External Application—Action on the Skin—Effects of the Vapour—Use of Carbolic Acid Lotions—Injections, &c.—Illustrative Cases, | 170-172 |
224. | Internal Administration—Illustrative Cases, | 173 |
225. | General Review of the Symptoms induced by Carbolic Acid, | 173, 174 |
226. | Changes Produced in the Urine by Carbolic Acid, | 174, 175 |
227. | The Action of Carbolic Acid considered Physiologically, | 175, 176 |
228. | Forms under which Carbolic Acid is Excreted, | 176 |
229. | Post-mortem Appearances, | 176, 177 |
| Tests for Carbolic Acid. | |
230. | (1) The Pine-Wood Test—(2) Ammonia and Hypochlorite Test—(3) Ferric Chloride—(4) Bromine, | 177, 178 |
231. | Quantitative Estimation of Carbolic Acid, | 178, 179 |
232. | Properties of Cresol, and Tests for Distinguishing Cresol and Carbolic Acid, | 179 |
233. | Properties of Creasote—Tests, | 179, 180 |
234. | Separation of Carbolic Acid from Organic Fluids or Tissues, | 180, 181 |
235. | Examination of the Urine for Phenol or Cresol, | 181 |
236. | Assay of Disinfectants, Carbolic Acid Powders—E. Waller’s Process—Koppeschaar’s Volumetric Method—Colorimetric Method of Estimation, | 181-183 |
237. | Carbolic Acid Powders, | 183 |
238. | Carbolic Acid Soaps, | 183 |
| X. NITRO-BENZENE. | |
239. | Properties and Varieties, | 183, 184 |
240. | Effects of Poisoning by Nitro-Benzene, | 184 |
241. | Illustrative Cases of Poisoning by Nitro-Benzene Vapour, | 184, 185 |
242. | Effects Produced by taking Liquid Nitro-Benzene, | 185, 186 |
243. | Fatal Dose, | 186, 187 |
244. | Pathological Appearances, | 187 |
245. | The Essential Action of Nitro-Benzene, | 187, 188 |
246. | Detection and Separation from the Animal Tissues, | 188 |
| XI. DINITRO-BENZOL. | |
247. | Properties of Ortho-, Meta-, and Para-Dinitro-Benzol, | 189 |
248. | Effects of Dinitro-Benzol, | 189, 190 |
249. | The Blood in Nitro-Benzol Poisoning, | 191 |
250. | Detection of Dinitro-Benzol, | 192 |
| XII. HYDROCYANIC ACID. | |
251. | Properties of Hydrocyanic Acid, | 192 |
252. | Medicinal Preparations of Prussic Acid—Various Strengths of the Commercial Acid, | 192, 193 |
253. | Poisoning by Prussic Acid—Uses in the Arts—Distribution in the Vegetable Kingdom, | 193-195 |
254. | Composition and Varieties of Amygdalin, | 195 |
255. | Statistics of Poisoning by Prussic Acid, | 195-197 |
256. | Accidental and Criminal Poisoning, | 197, 198 |
257. | Fatal Dose, | 198 |
258. | Action of Hydric and Potassic Cyanides on Living Organisms, | 198, 199 |
259. | Symptoms observed in Animals, | 199, 200 |
260. | Length of Interval between taking the Poison and Death in Animals, | 200, 201 |
261. | Symptoms in Man, | 201, 202 |
262. | Possible Acts after taking the Poison—Nunneley’s Experiments, | 202, 203 |
263. | Chronic Poisoning by Hydric Cyanide, | 203 |
264. | Post-mortem Appearances, | 203, 204 |
265. | Tests for Hydrocyanic Acid and Cyanide of Potassium—Schönbein’s Test—Kobert’s Test, | 204-206 |
266. | Separation of Hydric Cyanide or Potassic Cyanide from Organic Matters—N. Sokoloff’s Experiments, | 206-208 |
267. | How long after Death can Hydric or Potassic Cyanide be Detected? | 208, 209 |
268. | Estimation of Hydrocyanic Acid or Potassic Cyanide, | 209 |
269. | Case of Poisoning by Bitter Almonds, | 209, 210 |
| Poisonous Cyanides other than Hydric and Potassic Cyanides. | |
270. | General Action of the Alkaline Cyanides—Experiments with Ammonic Cyanide Vapour, | 210 |
271. | The Poisonous Action of several Metallic and Double Cyanides—The Effects of Mercuric and Silver Cyanides; of Potassic and Hydric Sulphocyanides; of Cyanogen Chloride; of Methyl Cyanide, and of Cyanuric Acid, | 210, 211 |
| XIII. PHOSPHORUS. | |
272. | Properties of Phosphorus—Solubility—Effects of Heat on Phosphorus, | 212, 213 |
273. | Phosphuretted Hydrogen—Phosphine, | 213 |
274. | The Medicinal Preparations of Phosphorus, | 213 |
275. | Matches and Vermin Paste, | 213-215 |
276. | Statistics of Phosphorus Poisoning, | 215, 216 |
277. | Fatal Dose, | 216 |
278. | Effects of Phosphorus, | 217 |
279. | Different Forms of Phosphorus Poisoning, | 217, 218 |
280. | Common Form, | 218, 219 |
281. | Hæmorrhagic Form, | 219 |
282. | Nervous Form, | 219 |
283. | Sequelæ, | 219, 220 |
284. | Period at which the First Symptoms commence, | 220 |
285. | Period of Death, | 220 |
286. | Effects of Phosphorus Vapour—Experiments on Rabbits, | 220, 221 |
287. | Effects of Chronic Phosphorus Poisoning, | 221, 222 |
288. | Changes in the Urinary Secretion, | 222 |
289. | Changes in the Blood, | 222, 223 |
290. | Antidote—Treatment by Turpentine, | 223 |
291. | Poisonous Effects of Phosphine, | 223, 224 |
292. | Coefficient of Solubility of Phosphine in Blood compared with Pure Water, | 224 |
293. | Post-mortem Appearances—Effects on the Liver, | 224-228 |
294. | Pathological Changes in the Kidneys, Lungs, and Nervous System, | 228 |
295. | Diagnostic Differences between Acute Yellow Atrophy of the Liver and Fatty Liver produced by Phosphorus, | 228, 229 |
296. | Detection of Phosphorus—Mitscherlich’s Process—The Production of Phosphine—Tests Dependent on the Combustion of Phosphine, | 229-232 |
297. | The Spectrum of Phosphine—Lipowitz’s Sulphur Test—Scherer’s Test, | 232, 233 |
298. | Chemical Examination of the Urine, | 233, 234 |
299. | Quantitative Estimation of Phosphorus, | 234 |
300. | How long can Phosphorus be recognised after Death? | 234, 235 |
|
| PART VI.—ALKALOIDS AND POISONOUS VEGETABLE PRINCIPLES SEPARATED FOR THE MOST PART BY ALCOHOLIC SOLVENTS. | |
| Division I.—Vegetable Alkaloids. | |
| I. GENERAL METHOD OF TESTING AND EXTRACTING ALKALOIDS. | |
301. | General Tests for Alkaloids, | 236 |
302. | Group-Reagents, | 236, 237 |
303. | Phosphomolybdic, Silico-Tungstic, and Phospho-Tungstic Acids as Alkaloidal Reagents, | 237-239 |
304. | Schulze’s Reagent, | 239 |
305. | Dragendorff’s Reagent, | 239 |
306. | Colour Tests, | 239 |
307. | Stas’s Process, | 239 |
| Methods of Separation. | |
308. | Selmi’s Process for Separating Alkaloids, | 240, 241 |
309. | Dragendorff’s Process, | 241-254 |
310. | Shorter Process for Separating some of the Alkaloids, | 254, 255 |
311. | Scheibler’s Process for Alkaloids, | 255 |
312. | Grandval and Lajoux’s Method, | 255, 256 |
313. | Identification of the Alkaloids, | 256 |
314. | Sublimation of the Alkaloids, | 256-261 |
315. | Melting-point, | 261 |
316. | Identification by Organic Analysis, | 261, 262 |
317. | Quantitative Estimation of the Alkaloids—Mayer’s Reagent—Compound of the Alkaloids with Chlorides of Gold and Platinum, | 262-264 |
| II. LIQUID VOLATILE ALKALOIDS. | |
| 1. The Alkaloids of Hemlock (Conium). | |
318. | Botanical Description of Hemlock, | 264 |
319. | Properties of Coniine—Tests, | 264-266 |
320. | Other Coniine Bases, | 266 |
321. | Pharmaceutical Preparations of Hemlock, | 266, 267 |
322. | Statistics of Coniine Poisoning, | 267 |
323. | Effects of Coniine on Animals, | 267, 268 |
324. | Effects of Coniine on Man, | 268 |
325. | Physiological Action of Coniine, | 268 |
326. | Post-mortem Appearances—Fatal Dose, | 268, 269 |
327. | Separation of Coniine from Organic Matters or Tissues, | 269 |
| 2. Tobacco—Nicotine. | |
328. | General Composition of Tobacco, | 269, 270 |
329. | Quantitative Estimation of Nicotine in Tobacco, | 270, 271 |
330. | Nicotine; its Properties and Tests, | 271-273 |
331. | Effects of Nicotine on Animals, | 273, 274 |
332. | Effects of Nicotine on Man, | 274, 275 |
333. | Some Instances of Poisoning by Tobacco and Tobacco Juice, | 275-277 |
334. | Physiological Action of Nicotine, | 277, 278 |
335. | Fatal Dose, | 278 |
336. | Post-mortem Appearances, | 278 |