514. | Symptoms Produced by Colchicum—Post-mortem Appearances, | 412, 413 |
515. | Separation of Colchicine from Organic Matters, | 413 |
| XIII. MUSCARINE AND THE ACTIVE PRINCIPLES OF CERTAIN FUNGI. | |
516. | Description of the Amanita Muscaria—Use of it by the Natives of Kamschatka, | 413, 414 |
517. | Cases of Poisoning by the Fungus itself, | 414, 415 |
518. | Muscarine—Its Properties and Effects, | 415, 416 |
519. | Antagonistic Action of Atropine and Muscarine, | 416 |
520. | Detection of Muscarine, | 416, 417 |
521. | The Agaricus Phalloides—Phallin, | 417 |
522. | Post-mortem Appearances, | 417, 418 |
523. | The Agaricus Pantherinus—The Agaricus Ruber—Ruberine—Agarythrine, | 418 |
524. | The Boletus Satanus, or Luridus, | 418 |
525. | Occasional Effects of the Common Morelle, | 418 |
| Division II.—Glucosides. | |
| I. DIGITALIS GROUP. | |
526. | Description of the Digitalis Purpurea, or Foxglove, | 419 |
527. | Active Principles of the Foxglove—The Digitalins, | 419 |
528. | Digitalein, | 420 |
529. | Digitonin—Digitogenin, | 420 |
530. | Digitalin, | 420 |
531. | Digitaletin, | 420 |
532. | Digitoxin—Toxiresin, | 420, 421 |
533. | Digitaleretin—Paradigitaletin, | 421 |
534. | Other Active Principles in Digitalis; such as Digitin, Digitalacrin, Digitalein, &c., | 421, 422 |
535. | Reactions of the Digitalins, | 422 |
536. | Pharmaceutical Preparations of Digitalin, | 422 |
537. | Fatal Dose, | 422-424 |
538. | Statistics of Poisoning by Digitalis, | 424 |
539. | Effects on Man—Illustrative Cases, | 424-427 |
540. | Physiological Action of the Digitalins, | 427 |
541. | Local Action of the Digitalins, | 427, 428 |
542. | Action on the Heart and Circulation, | 428, 429 |
543. | Action of the Digitalins on the Muco-Intestinal Tract and other Organs, | 429 |
544. | Action of Digitalin on the Common Blow-Fly, | 429 |
545. | Action of the Digitalins on the Frog’s Heart, | 429, 430 |
546. | Post-mortem Appearances, | 430 |
547. | Separation of the Digitalins from Animal Tissues, &c.—Tests, Chemical and Physiological, | 431 |
| II. OTHER POISONOUS GLUCOSIDES ACTING ON THE HEART. | |
| 1. Crystallisable Glucosides. | |
548. | Antiarin—Chemical Properties, | 432 |
549. | Effects of Antiarin, | 432 |
550. | Separation of Antiarin, | 432 |
551. | The Active Principles of the Hellebores—Helleborin—Helleborein—Helleboretin, | 433 |
552. | Symptoms of Poisoning by Hellebore, | 433 |
553. | Euonymin, | 433 |
554. | Thevetin, | 434 |
| 2. Substances partly Crystallisable, but which are not Glucosides. | |
555. | Strophantin, | 434 |
556. | Apocynin, | 434 |
| 3. Non-Crystallisable Glucosides almost Insoluble in Water. | |
557. | Scillain, or Scillitin—Adonidin, | 434 |
558. | Oleandrin, | 435 |
559. | Neriin, or Oleander Digitalin, | 435 |
560. | Symptoms of Poisoning by Oleander, | 435, 436 |
561. | The Madagascar Ordeal Poison, | 436 |
| 4. Substances which, with other Toxic Effects, behave like the Digitalins. | |
562. | Erythrophlein, | 436 |
| III. SAPONIN—SAPONIN SUBSTANCES. | |
563. | The Varieties of Saponins, | 436, 437 |
564. | Properties of Saponin, | 437 |
565. | Effects of Saponin, | 437, 438 |
566. | Action on Man, | 438 |
567. | Separation of Saponin, | 438, 439 |
568. | Identification of Saponin, | 439 |
| Division III.—Certain Poisonous Anhydrides of Organic Acids. | |
| I. SANTONIN. | |
569. | Properties of Santonin, | 439, 440 |
570. | Poisoning by Santonin, | 440 |
571. | Fatal Dose, | 440 |
572. | Effects on Animals, | 440 |
573. | Effects on Man—Yellow Vision, | 440, 441 |
574. | Post-mortem Appearances, | 441 |
575. | Separation from the Contents of the Stomach, | 441, 442 |
| II. MEZEREON. | |
576. | Cases of Poisoning by the Mezereon, | 442 |
| Division IV.—Various Vegetable Poisonous Principles—not Admitting of Classification Under the Previous Three Divisions. | |
| I. ERGOT OF RYE. | |
577. | Description of the Ergot Fungus, | 442, 443 |
578. | Chemical Constituents of Ergot—Ergotinine—Ecboline—Scleromucin—Sclerotic Acid—Sclererythrin—Scleroidin—Sclerocrystallin—Sphacelic Acid—Cornutin, | 443-445 |
579. | Detection of Ergot in Flour, | 445 |
580. | Pharmaceutical Preparations, | 445 |
581. | Dose, | 446 |
582. | Ergotism—Historical Notice of Various Outbreaks, | 446, 447 |
583. | Convulsive Form of Ergotism, | 447 |
584. | Gangrenous Form of Ergotism—The Wattisham Cases, | 447, 448 |
585. | Symptoms of Acute Poisoning by Ergot, | 448 |
586. | Physiological Action, as shown by Experiments on Animals, | 448-450 |
587. | Separation of the Active Principles of Ergot, | 450 |
| II. PICROTOXIN, THE ACTIVE PRINCIPLE OF THE COCCULUS INDICUS. | |
588. | Enumeration of the Active Principles contained in the Menispermum Cocculus, | 451 |
589. | Picrotoxin; its Chemical Reactions and Properties, | 451, 452 |
590. | Fatal Dose, | 452 |
591. | Effects on Animals, | 452, 453 |
592. | Effects on Man, | 453 |
593. | Physiological Action, | 453 |
594. | Separation from Organic Matters, | 453, 454 |
| III. THE POISON OF ILLICIUM RELIGIOSUM. | |
595. | Dr. Langaard’s Researches, | 454 |
| IV. PICRIC ACID AND PICRATES. | |
596. | Properties of Picric Acid, | 454 |
597. | Effects of Picric Acid, | 454, 455 |
598. | Tests, | 455 |
| V. CICUTOXIN. | |
599. | Description of the Cicuta Virosa, | 456 |
600. | Effects on Animals, | 456 |
601. | Effects on Man, | 456, 457 |
602. | Separation of Cicutoxin from the Body, | 457 |
| VI. ÆTHUSA CYNAPIUM (FOOL’S PARSLEY). | |
603. | Dr. Harley’s Experiments, | 457 |
| VII. ŒNANTHE CROCATA. | |
604. | The Water Hemlock—Description of the Plant—Cases of Poisoning, | 457, 458 |
605. | Effects of the Water Hemlock, as shown by the Plymouth Cases, | 458 |
606. | Post-mortem Appearances, | 459 |
| VIII. OIL OF SAVIN. | |
607. | Effects and Properties of Savin Oil, | 459 |
608. | Post-mortem Appearances, | 460 |
609. | Separation and Identification, | 460 |
| IX. CROTON OIL. | |
610. | Chemical Properties of Croton Oil, | 461 |
611. | Dose—Effects—Illustrative Cases, | 461 |
612. | Post-mortem Appearances, | 461 |
613. | Chemical Analysis, | 462 |
| X. THE TOXALBUMINS OF CASTOR OIL SEEDS AND ABRUS. | |
614. | The Toxalbumin of Castor Oil Seeds, | 462 |
615. | Toxalbumin of Abrus, | 462, 463 |
| XI. ICTROGEN. | |
616. | Ictrogen, | 463 |
| XII. COTTON SEEDS. | |
617. | Cotton Seeds as a Poison, | 464 |
| XIII. LATHYRUS SATIVUS. | |
618. | Poisonous Qualities of Vetchlings, | 464, 465 |
| XIV. ARUM—LOCUST-TREE—BRYONY—MALE FERN. | |
619. | Arum Maculatum, | 465 |
620. | The Black Bryony, | 465 |
621. | The Locust Tree, | 465 |
622. | Male Fern, | 465, 466 |
|
| PART VII.—POISONS DERIVED FROM LIVING OR DEAD ANIMAL SUBSTANCES. | |
| Division I.—Poisons Secreted by Living Animals. | |
| I. POISONOUS AMPHIBIA. | |
623. | Poisonous Properties of the Skin of the Salamandra Maculosa—Salamandrine, &c., | 467 |
624. | Poison from the Toad, | 468 |
| II. THE POISON OF THE SCORPION. | |
625. | Various Species of Scorpions—Effects of the Scorpion Poison, | 468 |
| III. POISONOUS FISH. | |
626. | Poisonous Fish—Illustrative Cases, | 468-470 |
| IV. POISONOUS SPIDERS AND INSECTS. | |
627. | The Bite of the Tarantula—The Bite of the Latrodectus Malmignatus, | 470 |
628. | Effects of the Bite of the Katipo, | 471 |
629. | Ants, &c., | 471 |
630. | The Poison of Wasps, Bees, and Hornets, | 471 |
631. | Cantharides, | 471 |
632. | Cantharidin, | 471, 472 |
633. | Pharmaceutical Preparations of Cantharides, | 472 |
634. | Fatal Dose, | 472 |
635. | Effects on Animals—Radecki’s Experiments—Effects on Man—Heinrich’s Auto-Experiments, | 472, 473 |
636. | General Symptoms Produced by Cantharides, | 473, 474 |
637. | Post-mortem Appearances, | 474 |
638. | Tests for Cantharidin—Distribution in the Body—Dragendorff’s Process, | 475-477 |
| V. SNAKE POISON. | |
639. | Classes of Poisonous Snakes, | 477 |
640. | The Poison of the Cobra, | 478 |
641. | Fatal Dose of Cobra Poison, | 479 |
642. | Effects on Animals, | 479 |
643. | Effects on Man, | 479, 480 |
644. | Antidotes and Treatment—Halford’s Treatment by Ammonia—Permanganate of Potash, | 480, 481 |
645. | Detection of the Cobra Venom, | 482 |
646. | Effects of the Bite of the Duboia Russellii, or Russell’s Viper, | 483 |
647. | The Poison of the Common Viper—The Venom of Naja Haje (Cleopatra’s Asp), | 483, 484 |
| Division II.—Ptomaines—Toxines. | |
648. | Definition of a Ptomaine, | 485 |
| Isolation of Ptomaines. | |
649. | Gautier’s Process, | 485 |
650. | Brieger’s Process, | 485-487 |
651. | Benzoyl Chloride Method, | 487, 488 |
652. | The Amines, | 488-490 |
653. | Methylamine, | 491 |
654. | Dimethylamine, | 491 |
655. | Trimethylamine, | 491 |
656. | Ethylamine, | 491 |
657. | Diethylamine, | 491 |
658. | Triethylamine, | 491 |
659. | Propylamine, | 491 |
660. | Isoamylamine, | 492 |
| Diamines. | |
661. | Rate of Formation of Diamines, | 492 |
662. | Ethylidenediamine, | 492 |
663. | Neuridine, | 493, 494 |
664. | Cadaverine, | 494-496 |
665. | Putrescine, | 496 |
666. | Metaphenylenediamine, | 497 |
667. | Paraphenylenediamine, | 497 |
668. | Hexamethylenediamine, | 497 |
669. | Diethylenediamine, | 497, 498 |
670. | Mydaleine, | 498 |
671. | Guanidine, | 498, 499 |
672. | Methylguanidine, | 499, 500 |
673. | Saprine, | 500 |
674. | The Choline Group, | 500, 501 |
675. | Neurine, | 501 |
676. | Betaine, | 501, 502 |
677. | Peptotoxine, | 502 |
678. | Pyridine-like Alkaloid from the Cuttle-fish, | 502, 503 |
679. | Poisons connected with Tetanus—Tetanine, | 503 |
680. | Tetanotoxine, | 503, 504 |
681. | Mydatoxine, | 504 |
682. | Mytilotoxine, | 505 |
683. | Tyrotoxicon, | 504, 505 |
684. | Toxines connected with Hog Cholera, | 505, 506 |
685. | Other Ptomaines, | 506 |
| Division III.—Food Poisoning. | |
686. | The Welbeck—The Oldham—The Bishop Stortford—The Wolverhampton—The Carlisle, and other Mass Poisonings by changed Food—Statistics of Deaths from Unwholesome Food, | 506-508 |
687. | German Sausage Poisoning, | 509 |
|
| PART VIII.—THE OXALIC ACID GROUP OF POISONS. | |
688. | Distribution of Oxalic Acid in the Animal and Vegetable Kingdoms, | 510 |
689. | Properties and Reactions of Oxalic Acid, | 510, 511 |
690. | Oxalate of Lime; its Properties, | 511, 512 |
691. | Use of Oxalic Acid in the Arts, | 512 |
692. | Properties of Hydropotassic Oxalate (Binoxalate of Potash), | 512 |
693. | Statistics of Oxalic Acid Poisoning, | 512 |
694. | Fatal Dose of Oxalic Acid, | 513 |