| 337. | Separation of Nicotine from Organic Matters, &c., | 278, 279 |
| | 3. Piturie. | |
| 338. | Properties of Piturie, | 279 |
| | 4. Sparteine. | |
| 339. | Properties of Sparteine, | 279, 280 |
| | 5. Aniline. | |
| 340. | Properties of Aniline, | 280 |
| 341. | Symptoms and Effects, | 280, 281 |
| 342. | Fatal Dose, | 281 |
| 343. | Detection of Aniline, | 281 |
| | III. THE OPIUM GROUP OF ALKALOIDS. | |
| 344. | General Composition of Opium, | 281, 282 |
| 345. | Action of Solvents on Opium, | 282, 283 |
| 346. | The Methods of Teschemacher and Smith, of Dott and others for the Assay of Opium, | 283, 284 |
| 347. | Medicinal and other Preparations of Opium, | 284-288 |
| 348. | Statistics of Opiate Poisoning, | 288, 289 |
| 349. | Poisoning of Children by Opium, | 289 |
| 350. | Doses of Opium and Morphine—Fatal Dose, | 289, 290 |
| 351. | General Method for the Detection of Opium, | 290, 291 |
| 352. | Morphine; its Properties, | 291, 292 |
| 353. | Morphine Salts; their Solubility, | 292, 293 |
| 354. | Constitution of Morphine, | 293, 294 |
| 355. | Tests for Morphine and its Compounds—Production of Morphine Hydriodide—Iodic Acid Test and other Reactions—Transformation of Morphine into Codeine, | 294-296 |
| 356. | Symptoms of Opium and Morphine Poisoning—Action on Animals, | 296-298 |
| 357. | Physiological Action, | 298, 299 |
| 358. | Physiological Action of Morphine Derivatives, | 299 |
| 359. | Action on Man—(a) The Sudden Form; (b) the Convulsive Form; (c) a Remittent Form of Opium Poisoning—Illustrative Cases, | 299-303 |
| 360. | Diagnosis of Opium Poisoning, | 303, 304 |
| 361. | Opium-Eating, | 304-306 |
| 362. | Treatment of Opium or Morphine Poisoning, | 306 |
| 363. | Post-mortem Appearances, | 306, 307 |
| 364. | Separation of Morphine from Animal Tissues and Fluids, | 307 |
| 365. | Extraction of Morphine, | 308, 309 |
| 366. | Narcotine; its Properties and Tests, | 309, 310 |
| 367. | Effects of Narcotine, | 310 |
| 368. | Codeine—Properties of Codeine, | 310, 311 |
| 369. | Effects of Codeine on Animals—Claude Bernard’s Experiments, | 311 |
| 370. | Narceine—Properties of Narceine—Tests, | 312, 313 |
| 371. | Effects of Narceine, | 313, 314 |
| 372. | Papaverine—Properties of Papaverine—Tests, | 314 |
| 373. | Effects of Papaverine, | 314 |
| 374. | Thebaine; its Properties, | 314, 315 |
| 375. | Thebaine; its Effects, | 315 |
| 376. | Cryptopine, | 315, 316 |
| 377. | Rhœadine, | 316 |
| 378. | Pseudomorphine, | 316 |
| 379. | Opianine, | 316 |
| 380. | Apomorphine, | 316, 317 |
| 381. | Reactions of some of the Rarer Opium Alkaloids, | 317 |
| 382. | Tritopine, | 317 |
| 383. | Meconin (Opianyl), | 317 |
| 384. | Meconic Acid—Effects of Meconic Acid—Tests, | 318, 319 |
| | IV. THE STRYCHNINE OR TETANUS-PRODUCING GROUP OF ALKALOIDS. | |
| | 1. Nux Vomica Group—Strychnine—Brucine—Igasurine. | |
| 385. | Nux Vomica—Characteristics of the Entire and of the Powdered Seed, | 319 |
| 386. | Chemical Composition of Nux Vomica, | 319 |
| 387. | Strychnine—Microscopical Appearances—Properties—Medicinal Preparations—Strychnine Salts, | 319-322 |
| 388. | Pharmaceutical and other Preparations of Nux Vomica, with Suggestions for their Valuation—Vermin-Killers, | 322-324 |
| 389. | Statistics, | 324-325 |
| 390. | Fatal Dose—Falck’s Experiments on Animals as to the Least Fatal Dose—Least Fatal Dose for Man, | 325-328 |
| 391. | Action on Animals—Frogs, | 328, 329 |
| 392. | Effects on Man—Symptoms—Distinction between “Disease Tetanus” and “Strychnos Tetanus,” | 329-331 |
| 393. | Diagnosis of Strychnine Poisoning, | 331, 332 |
| 394. | Physiological Action—Richet’s Experiments—The Rise of Temperature—Effect on the Blood-Pressure, | 332, 333 |
| 395. | Post-mortem Appearances, | 333 |
| 396. | Treatment, | 333 |
| 397. | Separation of Strychnine from Organic Matters—Separation from the Urine, Blood, and Tissues, | 334-337 |
| 398. | Identification of the Alkaloid—Colour Tests—Physiological Tests, | 337-339 |
| 399. | Hypaphorine, | 339 |
| 400. | Quantitative Estimation of Strychnine, | 339, 340 |
| 401. | Brucine; its Properties, | 340, 341 |
| 402. | Physiological Action of Brucine—Experiments of Falck, | 341, 342 |
| 403. | Tests for Brucine, | 342, 343 |
| 404. | Igasurine, | 344 |
| 405. | Strychnic Acid, | 344 |
| | 2. The Quebracho Group of Alkaloids. | |
| 406. | The Alkaloids of Quebracho—Aspidospermine—Quebrachine, | 344 |
| | 3. Pereirine. | |
| 407. | Pereirine, | 344, 345 |
| | 4. Gelsemine. | |
| 408. | Properties of Gelsemine, | 345 |
| 409. | Fatal Dose of Gelsemine, | 345 |
| 410. | Effects on Animals—Physiological Action, | 345 |
| 411. | Effects of Gelsemine on Man, | 346 |
| 412. | Extraction from Organic Matters, or the Tissues of the Body, | 347 |
| | 5. Cocaine. | |
| 413. | Cocaine; its Properties, | 47, 348 |
| 414. | Cocaine Hydrochlorate, | 348 |
| 415. | Pharmaceutical Preparations, | 348 |
| 416. | Separation of Cocaine and Tests, | 348, 349 |
| 417. | Symptoms, | 349 |
| 418. | Post-mortem Appearances, | 349, 350 |
| 419. | Fatal Dose, | 350 |
| | 6. Corydaline. | |
| 420. | Properties of Corydaline, | 350 |
| | V. THE ACONITE GROUP OF ALKALOIDS. | |
| 421. | Varieties of Aconite—Description of the Flower, and of the Seeds, | 350, 351 |
| 422. | Pharmaceutical Preparations of Aconite, | 351 |
| 423. | The Aconite Alkaloids, | 351 |
| 424. | Aconitine, | 351, 352 |
| 425. | Tests for Aconitine, | 352 |
| 426. | Benzoyl-Aconine Properties—Recognition of Benzoic Acid, | 353, 354 |
| 427. | Pyraconitine, | 354 |
| 428. | Pyraconine, | 354 |
| 429. | Aconine, | 355 |
| 430. | Commercial Aconitine—English and German Samples of Aconitine—Lethal Dose of the Alkaloid and of the Pharmaceutical Preparations, | 355-358 |
| 431. | Effects of Aconitine on Animal Life—Insects, Fish, Reptiles, Birds, Mammals, | 358-360 |
| 432. | Statistics, | 361 |
| 433. | Effects on Man, | 361 |
| 434. | Poisoning by the Root (Reg. v. M’Conkey), | 361, 362 |
| 435. | Poisoning by the Alkaloid Aconitine—Three Cases of Poisoning, | 363, 364 |
| 436. | Lamson’s Case, | 364, 365 |
| 437. | Symptoms of Poisoning by the Tincture, &c., | 365, 366 |
| 438. | Physiological Action, | 366 |
| 439. | Post-mortem Appearances, | 366, 367 |
| 440. | Separation of Aconitine from the Contents of the Stomach or the Organs, | 367, 368 |
| | VI. THE MYDRIATIC GROUP OF ALKALOIDS—ATROPINE—HYOSCYAMINE—SOLANINE—CYTISINE. | |
| | 1. Atropine. | |
| 441. | The Atropa belladonna; its Alkaloidal Content, | 368, 369 |
| 442. | The Datura stramonium—Distinction between Datura and Capsicum Seeds, | 369, 370 |
| 443. | Pharmaceutical Preparations—(a) Belladonna; (b) Stramonium, | 370, 371 |
| 444. | Properties of Atropine, | 371, 372 |
| 445. | Tests for Atropine, Chemical and Physiological, | 372-374 |
| 446. | Statistics of Atropine Poisoning, | 375 |
| 447. | Accidental and Criminal Poisoning by Atropine—Use of Dhatoora by the Hindoos, | 375, 376 |
| 448. | Fatal Dose of Atropine, | 376, 377 |
| 449. | Action on Animals, | 377 |
| 450. | Action on Man, | 377-380 |
| 451. | Physiological Action of Atropine, | 380 |
| 452. | Diagnosis of Atropine Poisoning, | 380 |
| 453. | Post-mortem Appearances, | 380 |
| 454. | Treatment of Cases of Poisoning by Atropine, | 380, 381 |
| 455. | Separation of Atropine from Organic Matters, &c., | 381 |
| | 2. Hyoscyamine. | |
| 456. | Distribution of Hyoscyamine—Properties, | 381-383 |
| 457. | Pharmaceutical and other Preparations of Henbane, | 383, 384 |
| 458. | Dose and Effects, | 384 |
| 459. | Separation of Hyoscyamine from Organic Matters, | 385 |
| | 3. Hyoscine. | |
| 460. | Hyoscine, | 385 |
| | 4. Solanine. | |
| 461. | Distribution of Solanine, | 385, 386 |
| 462. | Properties of Solanine, | 386 |
| 463. | Solanidine, | 386, 387 |
| 464. | Poisoning from Solanine, | 387 |
| 465. | Separation from Animal Tissues, | 387 |
| | 5. Cytisine. | |
| 466. | The Cytisus laburnum, | 387 |
| 467. | Reactions of Cytisine, | 388 |
| 468. | Effects on Animals, | 389 |
| 469. | Effects on Man—Illustrative Cases, | 389, 390 |
| | VII. THE ALKALOIDS OF THE VERATRUMS. | |
| 470. | The Alkaloids found in the Veratrum Viride and Veratrum Album—Yield per Kilogram, | 390-392 |
| 471. | Veratrine—Cevadine, | 392 |
| 472. | Jervine, | 393 |
| 473. | Pseudo-jervine, | 393 |
| 474. | Protoveratridine, | 393 |
| 475. | Rubi-jervine, | 394 |
| 476. | Veratralbine, | 394 |
| 477. | Veratroidine, | 394 |
| 478. | Commercial Veratrine, | 394, 395 |
| 479. | Pharmaceutical Preparations, | 395 |
| 480. | Fatal Dose, | 395 |
| 481. | Effects on Animals—Physiological Action, | 395, 396 |
| 482. | Effects on Man—Illustrative Cases, | 396 |
| 483. | Symptoms of Acute and Chronic Poisoning, | 396, 397 |
| 484. | Post-mortem Signs, | 397 |
| 485. | Separation of the Veratrum Alkaloids from Organic Matters, | 397 |
| | VIII. PHYSOSTIGMINE. | |
| 486. | The Active Principle of the Calabar Bean, | 397, 398 |
| 487. | Physostigmine or Eserine—Properties, | 398, 399 |
| 488. | Tests, | 399 |
| 489. | Pharmaceutical Preparations, | 399, 400 |
| 490. | Effects on Animals—On Man—The Liverpool Cases of Poisoning, | 400 |
| 491. | Physiological Action, | 401 |
| 492. | Post-mortem Appearances, | 401 |
| 493. | Separation of Physostigmine, | 401, 402 |
| 494. | Fatal Dose of Physostigmine, | 402 |
| | IX. PILOCARPINE. | |
| 495. | Alkaloids from the Jaborandi, | 402 |
| 496. | Pilocarpine, | 402, 403 |
| 497. | Tests, | 403 |
| 498. | Effects of Pilocarpine, | 403, 404 |
| | X. TAXINE. | |
| 499. | Properties of Taxine, | 404 |
| 500. | Poisoning by the Common Yew, | 404 |
| 501. | Effects on Animals—Physiological Action, | 404 |
| 502. | Effects on Man, | 404, 405 |
| 503. | Post-mortem Appearances, | 405 |
| | XI. CURARINE. | |
| 504. | Commercial Curarine—Properties, | 405-407 |
| 505. | Physiological Effects, | 407 |
| 506. | Separation of Curarine, | 407, 408 |
| | XII. COLCHICINE. | |
| 507. | Contents of Colchicine in Colchicum Seeds, | 408, 409 |
| 508. | Colchicine—Method of Extraction—Properties, | 409 |
| 509. | Tests, | 409, 410 |
| 510. | Pharmaceutical Preparations, | 410 |
| 511. | Fatal Dose, | 410, 411 |
| 512. | Effects of Colchicine on Animals, | 411 |
| 513. | Effects of Colchicum on Man—Illustrative Cases, | 411, 412 |
