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Clinical scenario

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A 45‐year‐old woman is admitted to hospital with severe urosepsis. She gives a background history of recurrent urinary infections and chronic renal impairment secondary to structural abnormalities of the urinary tract. Blood and urine culture reveals growth of Gram‐negative bacilli sensitive to gentamicin. How may this patient's renal function influence the treatment of her presenting complaint, and what precautions should be considered?

Clinical Pharmacology and Therapeutics

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