Читать книгу The Peripheral T-Cell Lymphomas - Группа авторов - Страница 106

Mycosis fungoides is the most common subtype of CTCL, accounting for approximately 50% of all primary CTCLs [83]. Like other lymphomas, it exhibits a male predominance with a ratio of two to one [84]. It is a disease affecting mostly older white populations, with a median age at diagnosis of 55–60 years [85]. Hispanic and African Americans typically present at a younger age, with most patients diagnosed by 40 years [51, 86]. A personal history of alcohol and tobacco use [87] and occupations such as carpentry, painting, textile industry, and farming are known to be associated with higher incidence of mycosis fungoides [88].

Sézary syndrome was initially thought to be a leukemic form of mycosis fungoides, but with advancement in histopathologic and genetic technique, is now classified as a separate entity. While the exact incidence is unknown it is thought to accounts for about 2–5% of CTCLs [85]. The incidence of Sézary syndrome is most common in non‐hispanic white populations [89]. Male predominance is noted with a male to female ratio of 2.1 : 1 [90].