Читать книгу Transfusion Medicine - Jeffrey McCullough - Страница 27

The relationship between bleeding and thrombocytopenia had been known for some time, but the development of the plastic bag system for blood collection made platelets available for transfusion. Several years of work by many investigators—predominantly at the National Cancer Institute during the 1960s—developed the methods for preparing platelets and established that platelet transfusion to patients with thrombocytopenia reduced mortality from hemorrhage [47]. Initially, platelets had to be transfused within a few hours after the whole blood was collected, and thus large‐scale application in the general medical care setting was impractical. The seminal report by Murphy and Gardner [48] showing that room temperature allowed platelets to be stored for several days revolutionized platelet transfusion therapy.