Читать книгу Transfusion Medicine - Jeffrey McCullough - Страница 29

As the benefits of platelet transfusion for thrombocytopenic patients were recognized, interest developed in using the same strategy to provide granulocyte transfusion to treat infection in patients with neutropenia. Initial attempts involved obtaining granulocytes from patients with chronic myelogenous leukemia [55, 56]. Transfusion of these cells had clinical benefits [57], and this led to a decade of effort to develop methods to obtain granulocytes from normal donors [58]. At best, these methods produced only modest doses of granulocytes; improvements in antibiotics and general patient care have supplanted the need for granulocyte transfusions except in very limited circumstances (see Chapters 10 and 11).