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In the United States, most platelets are produced by plateletpheresis, although a few are prepared from whole blood. In 2017, 2.259,000 units of platelets were provided. The number of plateletpheresis procedures was smaller because a median of 1.9 products were obtained from most procedures [26]. This is a 4.6% increase from 2015. Most (93.4%) platelets are prepared and stored in plasma and the remainder in platelet additive solutions [26]. Although most platelets are prepared by plateletpheresis, 221,000 units, or 9% of the supply were prepared, from whole blood (see Chapter 5). Apheresis platelets are used primarily, but as many as 19% were not used in 2017 [26].