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4.8.3 Improved Bioprocess Engineering
ОглавлениеProcess optimization plays a crucial role in cost reduction of large‐scale biosurfactant production. Synthesis of biosurfactant can be categorized into four foremost types:
1 Biosurfactant production associated with the growth medium and substrate utilization.
2 Under a growth‐limiting condition, biosurfactant production, e.g. P. aeruginosa shows an overproduction of biosurfactants when nitrogen and iron are limited.
3 Resting or immobilized cell utilization in biosurfactant production. This type of biosurfactant production shows high efficiency because microbial cells keep using a carbon source only for biosurfactant synthesis and not for multiplication, thus helping to reduce the production cost.
4 Precursor addition for biosurfactant production. The quality and quantity of biosurfactant polymer influenced chemical and physical parameters, and the type of carbon and nitrogen source along with their ratios in the culture media [64].