Читать книгу Biomolecular Engineering Solutions for Renewable Specialty Chemicals - Группа авторов - Страница 22

Topoisomerases change the affirmation of covalently closed circular DNA molecule, such as plasmids with the aid of removing the supercoils present in the round DNA molecule and alternate the linking number. It performs a major role in replication and transcription when the DNA unwinds, doing away with positive and negative supercoils (Liu, 1989).