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1.2.3.1.2 Transduction

Оглавление

Using phage particles for transferring foreign DNA into the host cells is called transduction. Therefore, it is also called as phage‐mediated gene transfer. It can be classified into generalized and specialized transduction. Generalized transduction involves phage particles attacking host cells and as the assembly of phage particles takes place host DNA gets packed inside them. When this phage particle infects another host cell, the DNA gets integrated into the host genome through recombination. While in specialized transduction, the phage genes get integrated with host genome and lysogenic cycle takes place. When some stimulus is given, the phage particles carry more than one genes from the host. These phage particles can infect a naive host cell by which the gene of interest can be inserted into the host genome.

Biomolecular Engineering Solutions for Renewable Specialty Chemicals

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